These tumors are less likely to spread to surrounding tissues than higher-grade tumors, so they often have better outcomes. In the past, pediatric gliomas were classified into low-grade and high-grade ...

Glioma is a tumor of the central nervous system that originates from glial cells, which support neurons in the brain. In the less aggressive, slow-progressing forms, gliomas are often found in ...

CLD-101, a stem cell-based platform, delivers oncolytic viruses to tumors, targeting high-grade glioma in a phase 1b/2 trial. Previous trials demonstrated CLD-101's safety and potential efficacy, with ...

Glioma, particularly glioblastoma, presents formidable challenges due to its infiltrative growth, resistance to conventional treatments and the protective blood–brain barrier that limits drug delivery ...

Recently, a team of South Korean researchers led by nuclear medicine physician and Professor Yun Mijin from Severance Hospital in collaboration with Director C. Justin LEE of the Center for Cognition ...

Expand and pull: A new treatment paradigm for glioblastoma using a long-acting recombinant interleukin-7 and oncolytic viral therapy. Out-of-pocket cost modeling of adjuvant radiation therapy duration ...

Pediatric low-grade gliomas (pLGGs) are a group of tumors that affect children, teenagers, and young adults. They are the most common tumors of the brain and spinal cord in young people. About 1 in 3 ...

The emergence of vorasidenib, the first targeted therapy for certain gliomas with IDH mutations, has ignited a wave of excitement in both patient and physician spaces. But following the approval, some ...

MedPage Today brought together three expert leaders for a virtual roundtable discussion on pediatric low-grade glioma. Moderator Jason Fangusaro, MD, of Emory University School of Medicine in Atlanta, ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...