Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 22 (May 29, 2018), pp. E5193-E5202 (10 pages) Store-operated Orai1 channels are activated through a ...
Results support the initiation of clinical studies to assess Orai1 inhibition in patients with recurrent acute pancreatitis (RAP) and early CP Data show that inhibiting Orai1-mediated store-operated ...
Preclinical data support CRAC channel inhibitor, CM5480, as a potential first-in-class, differentiated therapy for pulmonary arterial hypertension (PAH), both as monotherapy and in combination with ...
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