When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...

Mitochondria are well known as the powerhouses of the cell because of their energy generating capabilities. These little organelles are very special, because they also carry their own tiny little ...

Alphabet Inc.’s Google DeepMind today introduced AlphaGenome, a new artificial intelligence tool that can comprehensively predict how mutations or variants in human DNA sequences impact gene ...

Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including ...

The microbial toxin colibactin has just the right shape to snuggle up to DNA — but its embrace is unfortunately more cancerous than cozy. Colibactin is produced by bacteria in the gut and causes ...

Scientists have created a mega-database revealing how half a million different DNA mutations generate errors in proteins in humans. The researchers hope that the database will be used to develop new, ...