While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

Merck researchers developed a highly sustainable way to synthesize the macrocyclic peptide drug enlicitide, increasing ...

Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was published in Nature Communications. Subscribe to our newsletter for the ...

Researchers at the University of California, Santa Barbara, unveiled a new modular way to combine three mix-and-matchable molecular pieces into new amino acid derivatives using an engineered enzyme ...

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that ...

Photodynamic therapy (PDT), characterized by its non-invasive nature and precise spatiotemporal selectivity, has garnered considerable attention for its applications in tumor and anti-infection ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life—how enzymes are able ...

Structure of a twisting BINOL radical shown with a P450 enzyme in the background. A BINOL radical twists within a P450 enzyme. Credit: S. Luke Schulert Students of stereochemistry know that chirality ...