There are many chemical methods for adding medicinally helpful fluorinated alkyl groups onto molecules, but doing so with high stereoselectivity can be a challenge, especially at remote positions.

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...

Chemists have long dreamed of mimicking nature’s precision, and now, thanks to a repurposed enzyme, they’ve taken a leap closer. Researchers at the University of Basel have successfully combined a ...

Enzyme engineering is a significant tool for fine-tuning enzymes to alter their stability, activity, and specificity. Enzymes are highly versatile macromolecular biological catalysts that can ...

Synthetic chemists can go around in circles trying to make the cyclic amides known as lactams. That’s because lactams with 4-, 5-, and 6-membered rings—known as β-, γ- and δ-lactams, respectively—are ...

In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard Medical ...

Successful cancer surgery depends on a surgeon’s ability to remove tumors, while minimizing harm to healthy tissues. Surgeons currently use glowing dyes which mark cancer cells to help differentiate ...

Enzymes help with specific functions that are vital to the operation and overall health of the body. They help speed up chemical reactions in the human body. They are essential for respiration, ...