A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...

There are many chemical methods for adding medicinally helpful fluorinated alkyl groups onto molecules, but doing so with high stereoselectivity can be a challenge, especially at remote positions.

Scientists have prototyped a new method for 'rationally engineering' enzymes to deliver improved performance. They have devised an algorithm, which takes into account an enzyme's evolutionary history, ...

Chemists have long dreamed of mimicking nature’s precision, and now, thanks to a repurposed enzyme, they’ve taken a leap closer. Researchers at the University of Basel have successfully combined a ...

Enzyme engineering is a significant tool for fine-tuning enzymes to alter their stability, activity, and specificity. Enzymes are highly versatile macromolecular biological catalysts that can ...

In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard Medical ...

Newly discovered enzymes that are vital for bacterial defenses can also help chemists characterize the stereochemistry in natural products. The enzymes cut proteins between unusual amino acids, ...

Enzymes help with specific functions that are vital to the operation and overall health of the body. They help speed up chemical reactions in the human body. They are essential for respiration, ...