Tumors contain many different types of cells organized in complex spatial patterns that can influence how the disease progresses. Because of this, it is hard to predict how a tumor will develop and ...

The human genome contains about 23,000 genes, but only a fraction of those genes are turned on inside a cell at any given time. The complex network of regulatory elements that controls gene expression ...

The ability of different genetic variants—changes to one or more building blocks of DNA—to cause disease, and to what extent, ...

Engineered proteins that can cross the blood–brain barrier represent a reliable and non-invasive way to map gene expression in the brains of large animals. Gene therapy has been successfully used to ...

The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available. Researchers at Uppsala University have ...