The innate immune system is the first responder to disease or infection. The body employs non-specific immune cells to recognize foreign pathogens and immediately target these invaders by promoting an ...
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Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.
The current pandemic of COVID-19 has taken 1.5 million lives and counting while causing many more people to fall ill. Many studies have shown that adverse outcomes are related to excessive levels of ...
Pasithea Therapeutics announced promising preclinical data for PAS-004, a next-generation MEK inhibitor, which shows superior effectiveness in inhibiting the ETS2 pathway associated with ...
Medicine doesn’t have a great track record treating pancreatic cancer, with treatments like chemo and immunotherapy not making much headway. In a new mouse study from the Washington University School ...
Heart failure with preserved ejection fraction (HFpEF), a chronic inflammatory condition, is a leading cause of morbidity and mortality globally. Obesity, diabetes, and hypertension are highly ...
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Teas like green, ginger, rose hip, and fennel may help reduce inflammation through antioxidant compounds that combat oxidative stress.
Trial expansion into AGS and other Type 1 interferonopathies follows successful Phase 1a clinical trial of IMSB301 in healthy volunteers, which demonstrated a well-tolerated safety profile and ...
The whole-body MRI revealed similar inflammation levels in both patients with new arthralgia and those with new inflammatory arthritis after exposure to immune checkpoint inhibitors (ICIs), showing ...
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