Airway diseases such as asthma and chronic obstructive pulmonary disease arise from complex interactions between inhaled irritants and the mucosal immune system. Central to this interplay are ...

Sputum specialized proresolving mediators (SPMs), particularly resolvin D1 (RvD1), showed dynamic temporal changes and aided recovery during bacterial acute exacerbations of chronic obstructive ...

Leukotrienes are bioactive lipid mediators derived from arachidonic acid through the concerted action of lipoxygenase enzymes and associated proteins, orchestrating inflammatory initiation and ...

Image Caption: Pro-inflammatory cytokines and the C-X-C motif chemokine (CXC) family members and their receptors. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles ...

Monocytes are central to innate and adaptive immunity, regulating tissue homeostasis and inflammation. However, data on their ...

IRI is a shared pathological process in myocardial infarction, ischaemic stroke, acute kidney injury, lung injury, and graft dysfunction after transplantation.

In IAV-infected wild-type AECII, ELOVL5 promoted inflammation resolution and cell proliferation through both regulating lipid metabolism (promoting PUFAs generation while decreasing eicosanoid levels) ...

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...

Johns Hopkins Medicine researchers say they have identified molecular pathways controlled by the protein RhoA in club cells—a specialized population of epithelial cells that exclusively lines the ...

Inflammation is an immune response from the body’s immune system when there is a perceived injury or infection. When injured, inflammation causes the area to become red and swell due to a large number ...

“If you cut yourself and the wound gets infected, it’ll become inflamed. There’s a reason for that: The inflammation brings in all the white blood cells that help you fight the infection,” says Eric ...

Mary Choy, PharmD, BCGP, FASHP, is a pharmacist with board certification in geriatric pharmacotherapy. Supplements that support immune system function may help reduce inflammation in the body. Omega-3 ...