Genetic variants believed to cause blindness in nearly everyone who carries them actually lead to vision loss less than 30% ...

Many genetic variants linked to inherited eye disorders rarely lead to disease, meaning up to 2% of people could carry these variants without ever developing vision problems, according to a new s tudy ...

Two of Opus's seven gene therapy assets are in clinical trials, with additional programs expected to enter the clinic.

About the LUCE-1 Trial LUCE-1 is a Phase 1/2 multicenter, open-label, dose escalation study investigating safety, tolerability and preliminary efficacy of 3 dose levels of dual AAV8.MYO7A (AAVB-081) ...

Discovery of genetic glitches in gene formatting (RNU4-2 mutations) discloses a new cause for blindness, solving retinal ...

Researchers from Radboud university medical center and University of Basel have discovered new genetic causes of inherited ...

Retinal diseases are at the forefront of a quiet revolution in the realm of ophthalmology. Gene therapy, once a distant dream, is now emerging as a beacon of hope for millions affected by these ...

Please provide your email address to receive an email when new articles are posted on . Patients with inherited retinal diseases may present with seemingly routine conditions. Look for comorbid ...

Black patients with inherited retinal diseases who undergo genetic testing are less likely than White patients to receive a conclusive genetic diagnosis, new research shows. At one center, about 39% ...

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness. Investigators from Mass General Brigham used large public biobanks to determine that ...

Opus Genetics, Inc., a clinical-stage biotechnology company focusing on gene therapies for inherited retinal diseases, announced upcoming presentations at various scientific conferences in May 2025.

CHICAGO — Children with a rare, inherited retinal disorder who were treated with the first Food and Drug Administration-approved gene therapy had noticeable improvements in vision that may be related ...