Maps of protein–protein interactions (PPIs) become more elaborate as they incorporate richer troves of PPI data. In fact, these maps reflect a desire to be as comprehensive as possible, that is, to ...

No protein is an island. Proteins interact to keep the machinery of the whole organism running. Without protein-protein interactions (PPIs), there would be no biochemical reactions, transmission of ...

A recent study published in the WIRES journal summarized the importance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA)–protein interactomes in the study of RNA ...

It has been said that the journey of a thousand miles begins with a single step. Functional genomicists took that proverbial step earlier this month when a group led by Erich Wanker, of Berlin?s Max ...

Cerebellar ataxias form a large group of movement and balance disorders that result from degeneration of Purkinje cells. Nearly two dozen individual genes have been identified to date that, if mutated ...

Tau protein has long been implicated in neurodegenerative diseases. Mutations in the gene that encodes the Tau protein result in neurodegenerative conditions like frontotemporal dementia, while in ...

One of the fundamental goals of basic biology is understanding how diverse cell types work in concert to form tissues, organs, and organ systems. Recent efforts to catalog the different cell types in ...