Lipid nanoparticles (LNPs) are the leading nonviral nucleic acid delivery technology, but LNP structure-function data remains fragmented and nonstandardized. Unlike protein engineering which is ...

Lawrence Livermore National Laboratory researchers and a multi-institutional team of scientists have developed a highly detailed, machine learning-backed multiscale model revealing the importance of ...

We study lipid translocation (“flip-flop”) between the leaflets of planar lipid bilayers with artificial intelligence (AI) guided transition path sampling (TPS). Rare flip-flops compete with ...

Biological processes that govern our lives are many, intertwined, and often difficult to understand. They involve countless interactions happening at once—molecules recognizing each other, signals ...

Non-laboratory-based risk factors and lipids measured in adolescence independently predicted adult cardiovascular events, according to data from seven longitudinal cohort studies. In a multivariable ...