Liquid-liquid phase separation (LLPS) and crystallization are intertwined phenomena of considerable importance in both fundamental research and industrial applications, particularly in the ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

Video - Compilation of protein condensate formation. Full video available from Supplementary Information of the original article .

Under JST's Strategic Basic Research Programs, Noda Nobuo (Laboratory Head) and Fujioka Yuko (Senior Researcher) of the Institute of Microbial Chemistry, in collaboration with other researchers, ...

New findings could help scientists explain why hexanucleotide expansions in the C9ORF72 gene are the major cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). In ...

Scientists have discovered the first evidence of protein folding driven by liquid-liquid phase separation, a phenomenon in which fluids form into microscopic droplets and separate inside cells -- like ...

LLPS as a rising molecular entity in the cytoplasm regulates diseases progression via a variety of ways. For example, the relationship between LLPS and cancer can be summarized into six aspects: gene ...

Oil and water are both liquids, but they don't mix well, demonstrating a phenomenon known as liquid-liquid phase separation. In recent years, scientists have found that cells use phase separation, in ...

Liquid-liquid phase separation (LLPS) is a peculiar phenomenon that occurs during crystallization. In a new study, a group of researchers from Doshisha University, Japan, have investigated the ...