HF results in pulmonary and peripheral edema due to a decrease in cardiac output and retention of free water by the renal tubules. This fluid retention causes dyspnea, orthopnea and fatigue leading to ...

Loop diuretics are cornerstone therapies for the relief of congestion in patients with heart failure. By inhibiting the Na⁺‐K⁺‐2Cl⁻ cotransporter in the thick ascending limb of the loop of Henle, ...

BARCELONA, Spain—Patients with heart failure (HF) who are predicted to have a high risk of diuretic resistance tend to fare worse no matter whether they wind up taking furosemide or torsemide, with ...

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction ...

Future Cardiol. 2012;8(5):707-728. These data come from reports of ototoxicity of 6.4% with furosemide compared with 1 and <1% for bumetanide and torsemide, respectively. [38] Acute kidney failure is ...