Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis ...

In the choreography of meiosis—the process responsible for sex cell division in all eukaryotic life—the pairing of homologous chromosomes (homologs) is essential. Errors in this process can lead to an ...

The double-strand-break repair model (A) posits that during meiotic prophase I, crossovers (COs) and noncrossovers (NCOs) begin with a double-strand break (DSB) of a DNA helix. Cleavage of a structure ...

A new gene that controls the completion of meiosis in spermatogenesis has been discovered. Until now, details of the mechanism that inactivates the expression of genes involved in the meiotic program ...

Deletion of hsf5 in mice results in the impaired development of testis (left), and the absence of spermatids and spermatozoa (right), which leads to the failure of sperm formation. Kumamoto University ...