Alzheimer’s disease has long been the nightmare diagnosis that medicine could slow at best, not stop. Now a wave of ...

Technologies at the Advanced Rodent Transgenics Laboratory include genome editing design and implementation and transgenic ...

Using CRISPR-based technologies, the MoDeL team introduces precise genetic modifications in mice, enabling researchers to uncover how mammalian genes maintain health and contribute to disease.

Scientists stress out lab mice, a lot. Inducing chronic stress and anxiety in these furry critters is how scientists explore the bodily and cognitive effects of stress and discover anti-anxiety ...

A fundamental challenge in preclinical research is accurately predicting human responses using conventional animal models. Traditional approaches often fail to adequately model human disease, creating ...

Now a team of Brazilian scientists has put that tradition through a modern stress test: standardized extracts, controlled ...

Alzheimer’s is a multifaceted disease, particularly in its sporadic, late-onset form. Myriad factors—genetics, environment, cardiovascular health, metabolism, and inflammation—contribute to a ...

New research suggests that the commonly used ‘lab mouse’ may display behaviors entirely distinct from their wild-derived counterparts, prompting new considerations for the future of animal-based ...