Expression of the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (AGT), encoded by the O6-methylguanine (O6-mG) -DNA-methyltransferase (MGMT) DNA repair gene, results in resistance to ...
Expert Rev Mol Diagn. 2012;12(5):511-526. Qualitative end-point RT-PCR can be used for minimal residual disease (MRD) monitoring, [36] but has been largely overtaken by quantitative techniques that ...
Multiplex Ligation-dependent Probe Amplification (MLPA) is a method for detecting copy number changes using polymerase chain reaction (PCR). MLPA is unique in that it can detect copy number changes in ...
High complete remission rates are currently achieved in patients with acute myeloid leukaemia (AML). 1 However, many patients eventually relapse due to the emergence, persistence and finally outgrowth ...
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