The human leukocyte antigens (HLA-I) are multi-subunit complexes that localize to the cell surface and present bound peptides to nearby immune cells. The study of these HLA peptide-presenting ...

Researchers have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides -- chains of amino acids that are shorter than proteins, but perform similar ...

Researchers at the University of Toronto have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides – chains of amino acids that are shorter than proteins, ...

Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...

3D render of a molecular model. The molecule is alanine peptide. The shroud represents the region of hydrophobic repulsion, where the strength of the hydrophobic effect is approximately proportional ...

Peptides are short chains of amino acids that act as biological messengers, telling skin cells and tissues how to repair, ...

When it comes to developing a new medicine, designing the active compound is only half the battle. “Many potential therapeutic compounds are hydrophobic—oily—so they’re not very stable in aqueous ...