Protein drugs feature significant advantages over small molecule therapeutics, including low toxicity, high specificity, and development speed. However, the quality control requirements are ...

Proteins are the building blocks of life. These biomolecules comprise chains of amino acids that fold into precise shapes to ...

Researchers have developed a method to evaluate the folding stability of a million proteins simultaneously. DNA libraries were used to generate protein -- DNA complexes that were treated with enzymes ...

An innovative machine learning approach has been shown to rapidly predict multiple protein configurations. A new paper presents the method that predicts the relative populations of protein ...

Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...

Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers at Brown University has developed a way ...

Proteins are made of chains of amino acids, and a basic tenet of biology is that the sequence of amino acids determines how a protein folds into a 3D shape which, in turn, dictates the protein’s ...

For decades, scientists assumed that order drives efficiency. Yet in the bustling machinery of mitochondria—the organelles ...

U.S. and Canadian food labeling regulations require that protein digestibility be tested in rats to substantiate protein ...