Tissues are where most biological functions, drug effects and diseases occur, and are often considered a homogenous entity where different types of cells are woven in regularly repeated patterns.
Many spatial biology researchers rely on two-dimensional tools, which section the cellular architecture and processes occurring within 3D tissues into flat layers. Three-dimensional multiomic analysis ...
Sum-frequency generation (SFG) is a powerful vibrational spectroscopy that can selectively probe molecular structures at ...
Quantitative polymerase chain reaction (qPCR) is a molecular technique that has reshaped the landscape of biological research and medicine due to its high sensitivity and specificity. qPCR, also known ...
In a recent study posted to the medRxiv* preprint server, researchers used in situ sequencing and spatial single-cell transcriptome analysis (SSCTA) to examine postmortem coronavirus disease 2019 ...
Spatial genomics is a cutting-edge field that combines genomics and spatial analysis to investigate the role of genomic features in disease at single-cell resolution. Spatial genomics is a field of ...