A new EMBO Reports study suggests that obesity can leave a lasting epigenetic imprint on CD4 T cells, delaying the restoration of adaptive immune balance after weight loss. Using mouse models and ...
The immune system is the frontline protection against infection, continually searching for and destroying unknown pathogens.
Chronic kidney disease (CKD) and end‐stage renal disease (ESRD) are associated with profound alterations in the immune system, particularly affecting T lymphocytes. The decline in renal function ...
Invariant T cells, including mucosal-associated invariant T (MAIT) cells, invariant natural killer T (iNKT) cells and certain γδ T cell subsets, represent a unique arm of the immune system. These ...
T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...
Repertoire® Immune Medicines, a biotechnology company pioneering the discovery and development of programmable T cell-targeted immune medicines, today announced that the first participant has been ...
Lipid nanoparticle (LNP) mRNA vaccines induce robust immune responses and provide protection against infectious diseases. However, this immunity can be short-lived, resulting in the need for frequent ...
A detailed analysis of T-cell redirecting therapies in oncology, comparing the mechanisms of bispecific antibodies and CAR T ...
A new UCLA Health Jonsson Comprehensive Cancer Center study suggests that the way immune cells are organized inside melanoma ...
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