Autopsy has a central role in shedding light on diseases, helping to uncover the cause of death. Tissue samples from various organs are sampled, stained, and examined under a light microscope to ...

To date, examining patient tissue samples has meant cutting them into thin slices for histological analysis. This might now be set to change, thanks to a new staining method. This allows specialists ...

A research team has established an optimized three-dimensional (3D) tissue-staining and observation technique based on existing tissue clearing technology. The study details how the new technique can ...

An artificial intelligence-based method for virtual staining of histopathological tissue samples as a part of a new study is as effective as chemical staining. This virtually stained image can then be ...

Traditional histopathology, crucial for disease diagnosis, relies on chemically staining tissue samples to highlight cellular structures for microscopic examination by pathologists. This ...

The following article is the first of a three-part series on imaging large whole mount brain sections for neuroscience research. The series covers sectioning/staining, scanning, and data management.

Clearing methods allow light to penetrate samples for imaging, although the method used can affect tissue permeability to molecular probes. Conventional labeling protocols involve the slow diffusion ...

A RIKEN research team has established an optimized three-dimensional (3D) tissue-staining and observation technique based on existing tissue clearing technology. Published in Nature Communications, ...