Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...
From left: Charles Christoffer, Genki Terashi and Daisuke Kihara of Purdue University launched the high-tech software startup Molecular Intelligence to determine 3D structures of biomolecules. The ...
Discover how new developments in cryo-electron microscopy are set to transform biological imaging by supporting more targeted ...
Surface model of SpCas9–reverse transcriptase–pegRNA–target DNA complex. The prime editor, composed of a SpCas9 and a reverse transcriptase, reverse transcribes template sequence in pegRNA, resulting ...
Particles (encircled in green) are spaced at a distance from the noise surrounding the nanobeads (purple), which would otherwise obscure them. Sample loss has been a persistent problem in cryo-EM, a ...
Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, has revealed the high-resolution structures of amyloid fibrils directly ...
Using technologies like electron microscopy (EM) it is possible to capture molecular mechanisms in great detail, but not when these mechanisms are currently moving. The field of cryomicroscopy ...
RNA is thought to have sparked the origin of life by self-copying. Researchers have now revealed the atomic structure of an 'RNA copy machine' through cryo-EM. This breakthrough sheds light on a ...
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