The structure of a key enzyme involved in protein production is revealed by cryo-electron microscopy (cryo-EM). Using cryo-EM, researchers at Goethe University (Frankfurt, Germany) shed light on ...

Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new potential therapeutic target in tiny molecules called tRNA halves.

An international team of researchers including scientists from The Australian National University (ANU) have developed a way ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

The tRNA, part of our genetic code, acts as a molecular messenger crucial for building proteins, which are essential for the body's structure and function, it said, adding a mutation in tRNA can ...

An international team of researchers including scientists from The Australian National University (ANU) have developed a way to reveal the smallest ...

Archaeosine is a modified nucleoside found only in the tRNAs from archaea, the so-called third domain of life, and contributes to the maintenance of the L-shaped tRNA three-dimensional structure. The ...

In all living organisms, the biomolecule transfer RNA (tRNA) plays a fundamental role in protein production. tRNAs are generated from precursor molecules in several steps. The enzyme tRNA splicing ...

Loss of TRMT10A led to a decrease in the levels of initiator methionine tRNA (tRNA iMet) and a specific glutamine tRNA (tRNA Gln). This reduction weakened the initiation of protein synthesis for ...