Telomerase is an enzyme that helps maintain the telomeres, the caps at the end of each strand of DNA that protects the chronomose. Telomeres are like the plastic tips at the end of shoelaces, without ...

More than 30 years ago, when University of California, Berkeley researchers discovered telomerase - an enzyme that lengthens chromosome ends and prevents them from fraying enough to kill a cell - ...

Years after Elizabeth Blackburn, Ph.D. won the Nobel Prize for her seminal work on the molecular nature of telomeres and co-discovery of the ribonucleoprotein enzyme telomerase, scientists still ...

September 3, 2008 — It has been suggested that telomeres and telomerase are therapeutic targets in oncology, but many gaps remain in the understanding of their basic biology. However, in a study ...

(PHILADELPHIA) – Inappropriate activation of a single enzyme, telomerase, is associated with the uncontrollable proliferation of cells seen in as many as 90 percent of all of human cancers. Since the ...

A structural model of the telomerase enzyme shows how the binding domain (purple) tethers one end of the RNA component of the enzyme. (Image credit: Jansson et al., ) Researchers at UC Santa Cruz have ...

IN A MAJOR ADVANCE toward understanding a key biomolecule, scientists have solved the structure of the catalytic subunit of telomerase, the enzyme that maintains the length and integrity of telomeres, ...

Researchers have the molecular structure of telomerase. This should speed up the discovery of the best activators and inhibitors of telomerase. Good activators of telomerase has been shown to boost ...

In work that could help lead to anticancer therapeutics, researchers have obtained the first 3-D atomic structure of an essential part of the telomerase enzyme. Previously, telomerase could not be ...

Telomerase, because of its role in cancer and aging, has long been a target of drug companies who want to block it to stop the uncontrolled cell growth characteristic of cancer, or boost it to create ...

Inappropriate activation of a single enzyme, telomerase, is associated with the uncontrollable proliferation of cells seen in as many as 90 percent of all of human cancers. Scientists have long eyed ...

Researchers at UC Santa Cruz have determined the structure of a key part of the enzyme telomerase, which is active in most cancers and enables cancer cells to proliferate indefinitely. The new ...