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The first PPAR (PPARα) was discovered in 1990 during the search for a molecular target of a group of agents then referred to as peroxisome proliferators, as they increased peroxisomal numbers in …

Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor …

In this edition of Behind the Board, we're highlighting PPAR Director Eddie Hurt and sharing a few pieces of his journey that many members may not know. This series is all about introducing you to …

Jun 14, 2021 · In this Review, Staels and colleagues discuss the physiological regulation and actions of the PPAR family and their modulation of the atherogenic lipid profile, atherosclerosis and cardiac ...

The peroxisome proliferator activated receptor (PPAR) is a ligand activated nuclear receptor that participates in energy combustion via stimulation of lipid catabolism and energy storage via …

Apr 11, 2026 · Thereby, it exerts multifaceted protective actions against DKD. Although PPAR-targeted therapy is promising for DKD, critical knowledge gaps remain.

Apr 29, 2025 · Explore how PPAR signaling regulates metabolism, adipogenesis, and glucose balance through receptor subtypes, activation mechanisms, and pathway interactions.