Nurse Sarah on Instagram: "How to open ampules: nursing tips & tutorial. To open an ampule, first perform hand hygiene and the patient rights. Flick the ampule at the top to remove fluid. Use alcohol prep to clean the outside. Use gauze, alcohol prep, or an ampule opener to protect your fingers from cuts, and snap the ampule in a direction away from your body. Draw up the solution using a filter straw, being careful not to touch the outside. Remove the filter straw, and screw on the needle. Be s